Lead is lethal metal which can be used in different fields. Lead metal has a harmful influence on human care, it effect on all body systems. Lead nanoparticles (Pb NP) can be sensitized by different methods including chemical, physical, and biological methods. The furthermost inferior method is biological method owing to its ecofriendly, low cost, simple, not consume time, and not requisite luxurious tools. Pb NP entertainment as antimicrobial medications; this may perhaps in line for its capability to penetrate cell membrane of microbe, thus increase permeability of cell membrane, accumulation of Pb NP inside microbe. Once lead separated from Pb NP, it transfers in to respiratory system and bind with respiratory enzymes and deactivated them, leading to release free radicals, increase reactive oxygen species and cell destruction, so lead nanoparticles have a significant antimicrobial influence.
Walaa Fikry Elbossaty